My focus is student centred, imparting basic concepts while at the same time citing good examples to strengthen understanding.I cite examples of my learning in industry and develop a deep understanding of the subject in my students.
After my Masters in Life Sciences,I worked 14 years in the biotechnology industry. I taught for 11 years later completing my Doctoral degree. I am doing online content creation for clients of American universities and online classes on for post graduates.
To whomsoever it may concern,
It is with great interest that I am exploring employment opportunities at your organization. I am confident that my experience and skill sets would be an asset to your student’s learning and development. Education is vital to establishing a strong foundation on which understanding is based. The absence of education allows opportunities for ignorance to take form and grow, resulting in negative repercussions to society. Therefore, I aim to guide students in becoming mature, contributing members of our community. As a Lecturer, I have developed exceptional skills to encourage student participation in class through careful organization of teaching materials and engaging attitude. In my class, I believe all students should contribute to the learning process.
I have experience in providing visionary leadership to students; efficiently imparting quality management education to a wider range of aspiring professionals. I have exposure in facilitating social and intellectual growth of students by creating an atmosphere of mutual respect and students. I have proven competencies in designing course curriculum and implementing innovative instruction methodologies to match international standards
Details of my background and contributions are documented in the enclosed résumé, and it is with complete confidence that I present them as representative of the value and return on investment that I will bring to your organization.
Dr GAUTAM KRISHNAN, Ph.D
Dr. GAUTAM KRISHNAN
ACADEMICIAN/ RESEARCH AND DEVELOPMENT PROFESSIONAL - BIOTECHNOLOGY
Seeking a challenging opportunity with an organization of repute which utilizes my true potential in the field of Education
Dedicated, meticulous, resourceful and innovative professional; completed Ph.D. in “Functional
Characterization of Recombinant α-Crystallin of Mycobacterium tuberculosis H37Rv”and 24 years of rich academic & Research and Development experience in Biotechnology. Highly skilled in the application of modernized teaching & research methodology to generate far-reaching impact on the psyche of all levels of students and liberate hidden human potential.
Well versed in planning and organizing day-to-day research activities and resolve procedural problems as appropriate to the timely completion of research objectives.
Ability to effectively interact with diverse population of students at various academic levels. Skilled in recognizing, respecting and nurturing the creative potential of students and responding to all classroom queries in a spontaneous manner.
Demonstrated capabilities in conceptualizing, planning, and guiding R&D projects to evolve technological solutions and build strong base of patented products. Adept at designing and implementing quality systems/ procedures to ensure strict adherence to quality parameters.
Teaching ● Student Evaluation & Assessment ● Curriculum Design & Development ● Classroom Management
● R&D ● New Product Development ● Process Design & Validation ● Calibration/ Quality Control ● Project Management ● Technology Development
Freelance content creator
(November 2019- )
Creating online educational content for clients in the educational sector.
(May 2020- )
Teaching postgraduate students of biotechnology
GOA UNIVERSITY DEPARTMENT OF BIOTECHNOLOGY (September 2016- April 2017) Contributory Teacher
Taught theory courses like Food Biotechnology, Scientific Writing and Communication Skills for 1 semester (September-November 2016)
Taught theory courses like Environmental Biotechnology, Biosafety and IPR, Bioentreprenuership, Aquaculture Technology and Marine Pharmacology, (Dec 2016-April 2017) Guided 4 students to do MSc Dissertation.
BITS PILANI /KK BIRLA, GOA CAMPUS (Jan 2015 - Jun 2019) Research Scholar, Biological Sciences
Taught 16 lectures of Bioconversion Technology and ME Biotechnology course (August 2015-Dec 2015
Was Laboratory Instructor for following courses: Genetic Engineering (August 2016-December 2016); Genetic
Engineering and Experimental Techniques (January 2017 –April 2017) Biological Laboratory for 2 semesters –Jan
2015- April 2015; August 2017-Dec 2017; Jan 2018-April 2018
BITS PILANI/ KK BIRLA, GOA CAMPUS (December 2009 – December 2014) Visiting Faculty
Taught theory courses like General Biology for five semesters, Bioconversion Technology for three semesters and Recombinant DNA Technology for one semester.
Handled biology laboratory for seven semesters and worked as an Instructor in Charge for two semesters.
Explored and implemented innovative teaching techniques to accelerate learning process among students. Instructed students about the latest developments, principles and concepts of the field. Supervised the batch of students & maintained decorum amongst students.
Managed the class and supervised students as per the Institute’s policies, procedures and applicable laws. Prepared lectures and assignments/ examinations, graded them in a timely manner, and provided feedback to the students.
Actively worked with lecturers to develop, maintain high curriculum standards, and devise mission statements, and set performance goals and objectives
Collaborated with fellow lecturers on lesson plans and performed administrative tasks viz. recording attendance, managing student portfolios and providing individual assistance to the students
Identified areas of improvement while working with students and coached them to improve their performance consistently
Sample of Projects Supervised:
Application of image processing in biological processes (Angad Sachdev, Krishnan), January - April 2013
Software design for the optimization of biochemical process including storage of iterations and economic analysis of a product (Siddhant Srivastav), August - December 2012
Bio process control system and automation (Gurumurthi Ahad), August –December 2012
Downstream Purification of IgG (Soumya Rajan Sarangi, Rohit Shankar), August–December 2012
Use of software in DNA quantification (Adith Vastraaad and Shirish Kumar), January - April 2014
Use of software in Molecular Biology (Annesha Satpathi, Kapil Deep), January - April 2014
Use of neural network tools to predict of possibility of obtaining a clone (Natesh, Rohit Shiv Kumar, Siddarth, Sam), January-April 2014
DHEMPE COLLEGE OF ARTS AND SCIENCE MIRAMAR, GOA (June 2009 – December 2009) Lecturer - Biotechnology
Managed B.Sc. Biotechnology practical (Botany) for first year; B.Sc. Biotechnology practical, Environmental Biotechnology and Genetic Engineering for third year
GOODWIN BIOTECHNOLOGY INDIA, GOA (September 2006 – May 2009) Scientist I
Steered the R&D team working as a Contract Research organization and involved in servicing clients in the biotechnology and pharmaceutical industry with a team of 2 personnel
Accountable for undertaking assignments in research & managing analytical method development support for the study.
Performed research and data collection; conducted analysis to determine client’s technical and strategic needs.
Analyzed, summarized and presented results for all research projects. Reviewed ongoing research for trends.
Provided insight on these findings and ensured key findings are shared with appropriate internal audiences.
Identified issues and formed hypotheses, formulated and implemented solutions.
Established a new lab in Goa, India, the subsidiary of Florida-based, Goodwin Biotechnology Inc.
Undertook two and half-month training at GBI USA in fall 2006 to acquire experience in c-GMP.
Managed projects related to immunology specifically antibody purification and characterization and ELISA development.
Prepared Standard Operating Procedures for the new lab in India, obtained IQ, PQ and OQ documentation
BIOCON INDIA PVT LTD, BANGALORE (July 2001 – July 2006) Research Scientist
Administered the research & development team to develop new biological products of therapeutic value for the market with a team of 7 personnel
Title: To develop an industrial scale processes for making therapeutic proteins
Team Size: 7
The project was undertaken to develop lab scale process that could be scaled up to kg scale for production
Semi preparative scale up (10gm scale) protein purification experiments
Validated batches of downstream processes to establish proof of concept & for toxicity testing.
Participated in campaign to make clinical grade material for testing
Process development & optimized key ion exchange & reverse phase HPLC Steps
Impurity purification for submission to Quality Dept.
To work on Contract Projects for customers working in the Drug Discovery
Industry (Jul’01 –Apr’02)
Team Size: 3
The project was undertaken to study immunogenic proteins associated with cancer for expressing the protein in a soluble form
ASTRA ZENECA INDIA PVT LIMITED, BANGALORE (January 1995 – July 2001) Research Assistant/ Research Associate
Worked on Drug Discovery programs for malaria & antibiotics with a team of 5 personnel Possess knowledge of Cloning, Expression & Enzymatic Assays of Bacterial Proteins.
Facilitated screening 20000 compounds for an Anti-Malarial Drug Discovery program and in developing Enzymatic Assays for Anti Malarial Drug Discovery program and Anti Bacterial program.
Title: Anti-Malarial Project for development of Novel Anti-Malarial Drugs (Jan’95-Dec’99)
Team Size: 5
The project was undertaken to specify enzymes of malarial parasite, P. Falciparum with the idea of making rationally designed drugs. It was done by targeting development of an inhibitor against 3 protease – aspartic (Plasmepsin I, II) & cysteine (Plasmepsin II) of P. Falciparum
Managed Cloning, Hyper expression of Proteases
Refolded E. Coli inclusion body pellets to send to Queensland
Pharmacological Research Institute, Australia to screen natural extracts anti malarial.
Set up assays which can be adapted to medium and high throughput Format
Performed secondary screening of compounds identified from the 20000 screening campaign
Anti-bacterial Project (Helicase - DnaB) for the development of a broad-spectrum anti-bacterial for use in hospital infection & community care (Dec’99-Mar’01)
Team Size: 3
The project targeted the E. Coli Helicase–DnaB, Primary Replicate Helicase - The goal was to express DnaB in a soluble form and develop a gel based radioactive assay for the same which could later be used to screen potential anti bacterial compounds
PhD thesis “ Functional Characterization of Recombinant α-crystallin of Mycobacterium tuberculosis H37Rv”
BITS, Pilani, KK Birla Goa Campus(2019)
Masters in Biological Sciences, Birla Institute of Technology and Science, Pilani(1989-1994) Bachelors in Pharmacy, Birla Institute of Technology and Science, Pilani(1989-1994) KSET exam for Lecturer in Life Sciences (2018)
• Awarded with the Biocontribute Award (Team Award) in Dec’03; the team launched a therapeutic molecule for diabetes in market in Nov’04.
• Filed 2 patents in US,1 European patent(14 countries) and 2 Indian patents filed for manufacture of oral insulin.
• One of my students Rohit Shankar secured admission into Cornell University based on my recommendation. Others secured admission into Indiana University and Carnegie Mellon University.
• Passed 3 courses in Courseera-Learning How to Learn: Powerful mental tools to help you master tough subjects (McMaster University & University of California San Diego);Get Organised:How to be a together Teacher(Relay Graduate School of Education); The Challenges of Global Health( Duke University)
LIST OF PUBLICATIONS
1.Gautam Krishnan and Utpal Roy, “A New Functional Model for Prediction of Chaperone Activity of the Recombinant M. tb Acr (α-Crystallin) Using Insulin as Substrate,” Canadian Journal of Infectious Diseases and Medical Microbiology, vol. 2019, Article ID 2532045, 18 pages, 2019. (concealed information)
2. Krishnan, G., Roy, U. (2019). Role of Molecular Interactions and Oligomerization in Chaperone Activity of Recombinant Acr from Mycobacterium tuberculosis. Iranian Journal of Biotechnology, 17(3), 55-62. doi:
3. Krishnan G and Roy U. Prediction of recombinant Mycobacterium tuberculosis α-crystallin oligomer chaperone activity using polynomial graphs [version 2; peer review: 2 approved]. F1000Research 2020, 7:1801 ((concealed information)
1. Title of paper “Cloning and expression of antigenic proteins of pathogenic organisms: special focus on
Mycobacterial family” by Dr Utpal Roy, Gautam Krishnan, Sam C., Joy B., Natesh, Siddharth T., Rohit
Shivkumar presented at NATCON 2014 – Feb 7th, 2015, Mumbai
2. Conference presentation: Key note speaker “A functional model for predicting in vitro chaperone
activity of M. tb Acr” at 3rd International Conference of Clinical Microbiology, Kyoto, Japan, May 1st - 2nd, 2019
Clin Microbiology,2019,Vol 8 doi 10.4172/2327-5073-C2-047
Nitesh Dave, Partha Hazra, Anuj Goel, Nita Roy, Anand Khedkar, Harish Iyer, Gautam Krishnan, H S Manjunath, Shrikumar Suryanarayan, Govindasamy Manikam, Goldy Sachdev, Mayank Garg: Process for the preparation of insulin conjugate IN -105. Biocon. Nov, 15 2011: US8058391 (B2)
Partha Hazra, Manjunath Hadavanahalli Shivarudraiah, Anand Khedkar, Harish Iyer, Nitesh Dave, Gautam Krishnan, and Shrikumar Suryanarayan: Preparation of insulin conjugates. Biocon. Jul, 12 2011:
US7977454 (B2) Nitesh Dave, Partha Hazra, Anuj Goel, Nita Roy, Anand Khedkar, Harish Iyer, Gautam Krishnan, H. S. Manjunath, Shrikumar Suryanarayan, Govindasamy Manikam, Goldy Sachdev, Mayank Garg, Process for the
preparation of insulin conjugates EP 1934252 B1-Renewed in 14 European countries as of 2018.Same as CN(concealed information)A,CN(concealed information)B, EP1934252A1, EP1934252A4, US8058391, US2(concealed information), WO
Nitesh Dave, Partha Hazra, Anuj Goel, Nita Roy, Anand Khedkar, Harish Iyer, Gautam Krishnan, H S Manjunath, Shrikumar Suryanarayan, Govindasamy Manikam, Goldy Sachdev, Mayank Garg: Process for the preparation of insulin conjugates . Indian Patent No :283452
Partha Hazra, HS Manjunath, Anand Khedkar, Harish Iyer, Nitesh Dave, Gautam Krishnan, and Shrikumar Suryanarayan:Preparation of Insulin conjugates Indian Patent No:253674
Date of Birth: 3 July 1971
References: Available on request
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