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Lessons offered by Brile
  • Individual
The lessons will be held
  • Chez le professeur
  • at your home
Taught subjects
  • Biology
  • Cell biology
  • Microbiology
  • Biotechnology
  • College / University Preparation
Levels
  • Sophomore
  • Junior
  • Senior
  • Advanced Technical Certificate
  • College / University
  • Adult Education
  • MBA

Dr. Brile Chung will teach basic and advance biology in Pasadena and San Marino areas

Methodology

PROFESSIONAL EDUCATION

Fellowship: Stanford University Division of Stem Cell Transplantation (2009)

Ph.D., University of Southern California (2005)

M.S., California State University, Los Angeles (2001)

B.S. University of California, San Diego (1994)


HONORS & AWARDS

Ernest McCulloch and James Till Award for the best science article in Biology of Blood and Marrow Transplantation by a new investigator, American Society for Blood and Marrow Transplantation, (ASBMT) Annual Meeting, San Diego, CA, 2012
Invention: U.S. Provisional Patent: IL-7 receptor blockade to suppress immunity, CHLA Ref: 03-06; Ref. No: 9022.44PR, 2006
Children’s Hospital Los Angeles Research Institute Poster Award, 2005.

The American Society of Hematology Travel Award, 2003.

Graduate Honorary Award (California State University of Los Angeles), 2001.
Children’s Hospital Los Angeles Research Institute Poster Award, 1999.
The American Society of Hematology Travel Award, 1999.
The American Society of Hematology Travel Award, 1998.
APPOINTMENTS
Assistant research professor, Department of Immuno-Oncology at City of Hope (2013 – 2017)
Staff Scientist, Department of Immuno-Oncology at City of Hope (2012 – 2013)
Junior Faculty, Department of Pathology and Laboratory Medicine, Broad Stem Cell Research Center, UCLA, David Geffen School of Medicine, UCLA (2011 – 2012)

PROFESSIONAL ACTIVITIES:
Consulting activities: Scientific Consultant and Reviewer (for hematopoietic and mesenchymal stem cells), BioLegends, 2010 - Present
F1000 Associate Faculty Member/Post-publication peer review (since 10 November 2010). Assigned to review 5 to 10 post-publication peer review, 2010 - 2012
Professional and scholarly associations: Membership in American Society for Blood and Marrow Transplantation.
Teaching: Cal State University of Los Angeles: Immunology, 2000.

EDITORIAL SERVICES TO SCHOLARLY PUBLICATIONS:
Stem Cells (May 2009-Present)

Human Gene Therapy (August 2011)

Journal of cardiovascular translational research (Oct 2010)






Background

I am a former assistant research professor from the Dept. of Immuno-Oncology at City of Hope. Besides designing experiments and writing peer-reviewed scientific manuscripts during my 20 plus years as a cell biologist/immunologist, my ability to develop positive relationships with many students (both under and graduate), post-doctoral fellows, and scientific peers enabled me to be a great teacher, lecturer, and motivator to the various institutions I had a privilege to serve.

During my Post-doctoral research studies under the direction of Kenneth I Weinberg, M. D., Stanford University, School of Medicine, Department of Pediatrics, Division of Stem Cell Transplantation, I taught and mentor many rotating undergraduate and graduate students about various aspects of immune regulation and immune reconstitution utilizing hematopoietic stem cell (HSC) transplantation model system. Teaching them the basic aspects of T cell development, these students were able to learn and apply their knowledge very effectively through presentations (nationally). Through these studies, I also have extended my knowledge to teach both cellular and molecular aspects of T cell development, immuno-regulation of mature T cells, and development of organoid models from human and murine embryonic stem cells.

As a faculty member (at UCLA and City of Hope), I promoted students to assume a very active responsibility for their own scientific learning. These motivated students happily made strategic choices, reflected on their own learning processes, collaborated with other students and submitted constant scientific input. All my students understood what they were learning, why they were learning it, and how it applied to the scientific communities beyond the research institute or classroom. It was great pleasure to watch every undergraduate student I taught ended up attending medical and graduate school. I also had the opportunity to teach immunology at Cal State Los Angeles as a visiting scholar, working closely with both departmental faculty members.

As an assistant professor, I truly believe that developing teacher-student relationships by constantly motivating students to incorporate scientific knowledge they’ve learned to modern scientific world. I am a lifelong learner and would love the opportunity to share my belief with the students. Thank you for considering my application, and I hope to discuss with you how my knowledge and experience can best meet the goals.

Sincerely,

Brile Chung

Rates

Transportation Fee : $80
Lessons offered by Brile
Individual
The lessons will be held
Chez le professeur
at your home
Taught subjects
  • Biology
  • Cell biology
  • Microbiology
  • Biotechnology
  • College / University Preparation
Levels
  • Sophomore
  • Junior
  • Senior
  • Advanced Technical Certificate
  • College / University
  • Adult Education
  • MBA

Brile's resume

CURRICULUM VITAE
NAME: Brile Chung, Ph.D. EDUCATION:
1994 University of California, San Diego B.S. (Biology)
2001 California State University, Los Angeles M.S. (Biology)
2005 University of Southern California
Ph.D. (Craniofacial Molecular Biology /Stem Cell Biology)
2009 Stanford University
Post-doctoral fellowship (Division of Stem Cell Transplant)
2010 University of California, Los Angeles Post-doctoral fellowship (Division of Pathology)
PROFESSIONAL EXPERIENCE:
Present: Assistant research professor (Department of Immuno-Oncology at City of Hope) Previous positions:
2(concealed information)2-2(concealed information)2
20(concealed information)-20(concealed information) 1995 1994-1995 1992-1993
Assistant research professor (Department of Cancer Immuno-therapeutics & Tumor Immunology at City of Hope)
Staff Scientist (Department of Cancer Immuno-therapeutics & Tumor Immunology at City of Hope)
Junior Faculty (Department of Pathology and Laboratory Medicine, Broad Stem Cell Research Center, UCLA, David Geffen School of Medicine, UCLA)
Post-doctoral fellowship, University of California, Los Angeles (Dept. of Pathology) Post-doctoral fellowship, Stanford University (Dept. of Pediatrics, Stem cell Transplant) Research Assistant, Children’s Hospital Los Angeles (Division of BMT/Immunology) Research Assistant, Scripps Research Institute, CA
Lab Assistant, University of California, San Diego Lab Assistant, Salk Institute, CA
1
PROFESSIONAL ACTIVITIES:
Consulting activities: Scientific Consultant and Reviewer (for hematopoietic and mesenchymal stem cells), BioLegends, 2010 - Present.
F1000 Associate Faculty Member/Post-publication peer review (since 10 November 2010). Assigned to review 5 to 10 post-publication peer review, 2010 - 2012
Professional and scholarly associations: Membership in American Society for Blood and Marrow Transplantation.
Teaching: Cal State University of Los Angeles: Immunology, 2000.C
HONORS AND SPECIAL AWARDS:
Ernest McCulloch and James Till Award for the best science article in Biology of Blood and Marrow Transplantation by a new investigator, American Society for Blood and Marrow Transplantation, (ASBMT) Annual Meeting, San Diego, CA, 2012
Invention: U.S. Provisional Patent: IL-7 receptor blockade to suppress immunity, CHLA Ref: 03-06; Ref. No: 9022.44PR, 2006
Childrens Hospital Los Angeles Research Institute Poster Award, 2005.
The American Society of Hematology Travel Award, 2003.
Graduate Honorary Award (California State University of Los Angeles), 2001. Childrens Hospital Los Angeles Research Institute Poster Award, 1999.
The American Society of Hematology Travel Award, 1999. The American Society of Hematology Travel Award, 1998.
EDITORIAL SERVICES TO SCHOLARLY PUBLICATIONS (e.g., serving as a reviewer or editor) Stem Cells (May 2009-Present)
Human Gene Therapy (August 2011)
Journal of cardiovascular translational research (Oct 2010)
2
RESEARCH GRANTS AND FELLOWSHIPS RECEIVED:
CIRM Stem Cell Transplantation Immunology Awards (1707): Engineering Thymic Regeneration to Induce Tolerance, 2010 -2013 (PI: Gay Crooks and Scientific team Talal Chatila, and Brile Chung [$1.2 million]).
Stanford University Dean’s Fellowship. 2008-2009 (1(concealed information)KAUMZ, PI: Brile Chung). Generation of thymic epithelial cells by human embryonic stem cells ($50,000.00).
RESEARCH PAPERS (Scientific Peer-Reviewed)
1. Chung B, Barbara-Burnham L, Barsky L, Weinberg K. Radiosensitivity of thymic interleukin-7
production and thymopoiesis after bone marrow transplant. Blood. 2001. 98:1601-06.
2. Min D, Taylor PA, Panoskaltsis A, Chung B, Danilenko DM, Farrell C, Lacey DL, Blazar BR, Weinberg KI. Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation. Blood. 2002;99:4592-4600.
3. Chung B, Dudl E, Min D, Barsky L, Smilely N, Weinberg K. Prevention of graft-versus-host disease by anti-IL-7Rα antibody. Blood. 2007;110(8): 2803-10.
4. Chung B, Dudl E, Toyama A, Barsky L, Weinberg K. Importance of IL-7 in the development of experimental graft-versus-host disease. Biol. Blood Marrow Transplant. 2008;14(1):16-27
5. Ren YX, Finckenstein FG, Abdueva DA, Shahbazian V, Chung B, Weinberg KI, Triche TJ, Shimada H, Anderson MJ. Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with second mutations. Cancer Res. 2008;68(16):6587-6597.
6. Huang g, Pshmforoush M, Chung B, Saxon LA. The role of cardiac electrophysiology in myocardial regenerative stem cell therapy. J Cardiovasc Transl Res. 2011;4(1):61-65.
7. Chung B, Min D, Krampf MR, Joo WJ, Huang J, Yang Y et. al. Combined effects of IL-7 and SCF administration on lymphopoiesis after murine bone marrow transplantation. Biol Blood Marrow Transplant. 2011 Jan;17(1):48-60.
8. Chung B, Stuge TB, Murad J, Beilhack G, Johannsen A, Andersen E, Weber JS, Lee PP. Immune regulation of high avidity T-cells by low avidity T-cells via trogocytosis effects target cell cytotoxicity and anti-tumor activity. Cell Rep. 2014;8(3):871-82.
9. Chung B, Ge S, Zhu J, Parekh C, Blumberg G, Arumugam B, Yang O, and Crooks GM. Engineering the human thymic microenvironment to support thymopoiesis in vivo. Stem Cells. 2014;32(9):2386-96.
10. Chung B, Esmaeili A, Murad JP, Andersen E et al. Human brain metastatic stroma attracts breast cancer cells via chemokines CXCL16 and CXCL12. npj Breast Cancer (2017) 3:6 ; doi:10.1038/s(concealed information)08.
Chung B, Reddy N, Chu C, Esmaeili A et al. The use of EGFR-CD3 bispecific antibody and antigen- specific high avidity CTL to target cancer associated fibroblasts and cancer cells within a melanoma organoid model system (manuscript in preparation).
3
LECTURES AND PRESENTATIONS:
1. Chung B, Barbara-Burnham L, Barsky L, Weinberg K. Radiosensitivity of thymic IL-7 production and
thymopoiesis after murine bone marrow transplant (BMT). Exp Hematol 26:686a, 1998.
2. Chung B, Barbara-Burnham L, Barsky L, Weinberg K. Thymic IL-7 production is radiosensitive and is related to thymic recovery after murine bone marrow transplant (BMT). American Society of Hematology, 1998.
3. Chung B, Barbara-Burnham L, Barsky L, Weinberg K. Generation of T lymphocytes in thymectomized BMT recipients co-transplanted with stromal cells transduced with IL-7 gene. American Society of Hematology, 1999.
4. Chung B, Min D, Barbara-Burnham L, Barsky L, Weinberg K. Stimulation of T-lymphopoiesis in thymectomized bone marrow transplant (BMT) recipients treated with stromal cells retrovirally transduced with the IL-7 gene. Mol Ther 1:S250, 2000.
5. Chung B, Min D, Barbara-Burnham L, Barsky L, Weinberg K. Recapitulation of thymic ontogeny and immune reconstitution in thymectomized murine BMT recipients after IL-7 gene therapy. FASEB Journal 14:a921, 2000.
6. Min D, Taylor P, Chung B, Panoskaltsis-Mortari A, Farrell C, Lacey D, Blazar B, Weinberg K. Protection from thymic epithelial cell (TEC) injury by pre-BMT keratinocyte growth factor (KGF): a new approach to speed thymic reconstitution after lethal irradiation. American Society of Hematology, 2000.
7. Toyama A, Chung B, Brown J, Weinberg KI. The IL-7R and c-kit receptors provide more than survival signals in thymic differentiation. American Society of Hematology, 2002.
8. Chung B, Dudl E, Toyama A, Barsky L, Price M, Weinberg KI. IL-7 is necessary for induction of experimental graft-versus-host disease. American Society of Hematology, 2003.
9. Dudl E, Toyama A, Arber C, Bit-Mansour A, Brown J, Chung B, Price M, Brown J, Weinberg KI. Regulation of common lymphoid progenitors (CLP) by common gamma (C) and C-kit signals in vivo. American Society of Hematology, 2003.
10. Chung B, Dudl E, Toyama A, Barsky L, Weinberg KI. IL-7 is required for the development of graft- versus-host disease. FASEB Journal, 2004.
11. Dudl E, Toyama A, Arber C, Bit-Mansour A, Brown J, Chung B, Price M, Brown J, Weinberg KI. FASEB Journal, 2004.
12. Chung B, Dudl E, Toyama A, Barsky L, Price M, Weinberg KI. IL-7 is a necessary factor for induction of experimental graft-versus-host disease. American Society for Blood and Marrow Transplant, 2004.
13. Chung B, Joo W, Smiley N, Barsky L, Weinberg KI. IL-7 treatment after early blockade of IL-7 results in prevention of graft-versus-host disease and enhancement of immune reconstitution. FASEB Journal, 2005.
14. Dudl E, Toyama A, Arber C, Bit-Mansour A, Brown J, Chung B, Price M, Brown J, Weinberg KI. 4

FASEB Journal, 2005. Common gamma chain and C-kit signals are important for survival and proliferation of early hematopoietic and lymphoid progenitors. FASEB Journal, 2005.
15. Chung B, Dudl E, Joo W, Smiley N, Barsky L, Weinberg KI. IL-7 blockade prevents graft-versus-host diease and improves T cell reconstitution following allogeneic bone marrow transplantation. American Society of Hematology, 2005.
16. Min D, Chung B, Huang J, Butte A, and Weinberg KI. Age-related perturbation of thymic epithelial cells (TEC) homeostasis is caused by increased TNFR/Fas-mediated apoptosis coupled with decreased proliferation. American Society of Hematology, 2008.
17. Chung B, Min D, Krampf M, Ju WJ, Weinberg KI. Enhancement of T cell development in murine bone marrow transplant recipients by transfer of the IL-7 or SCF gene into marrow-derived mesenchymal stem cells. American Society of Hematology, 2008.
18. Shashidhar S, Chung B, Huang J, Krampf M, Brown J, Weinberg KI. Effects of IL-7 on Dynamics of T- Cell Recovery After Transplantation with Purified HSC and Common Lymphoid Progenitors (CLP). American Society of Hematology, 2009.
19. Kenneth Weinberg, Dullei Min, Shivkumar Venkatasubrahmanyam, Brile Chung, Yujun Yang, Christine Goetz, Brent Winston, Mark Krampf, Jason Karamchandani, Bruce Blazar, Atul Butte. Convergence of NF- B-mediated inflammatory and HNF4α-mediated metabolic signaling networks in age- related thymic involution. J Immunol2014;192:116.5, May 1, 2014.
5

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